Nerve injury-induced tactile allodynia is present in the absence of FOS labeling in retrogradely labeled post-synaptic dorsal column neurons
ET Zhang, MH Ossipov, DQ Zhang, J Lai, F Porreca - Pain, 2007 - Elsevier
The dorsal column pathway consists of direct projections from primary afferents and of
ascending fibers of the post-synaptic dorsal column (PSDC) cells. This pathway mediates
touch but may also mediate allodynia after nerve injury. The role of PSDC neurons in nerve
injury-induced mechanical allodynia is unknown. Repetitive gentle, tactile stimulus or
noxious pinch was applied to the ipsilateral hindpaw of rats with spinal nerve ligation (SNL)
or sham surgery that had previously received tetramethylrhodamine dextran in the ipsilateral …
ascending fibers of the post-synaptic dorsal column (PSDC) cells. This pathway mediates
touch but may also mediate allodynia after nerve injury. The role of PSDC neurons in nerve
injury-induced mechanical allodynia is unknown. Repetitive gentle, tactile stimulus or
noxious pinch was applied to the ipsilateral hindpaw of rats with spinal nerve ligation (SNL)
or sham surgery that had previously received tetramethylrhodamine dextran in the ipsilateral …
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